Tag: Development of Vaccines

Development of vaccines can be simplified into two broad stages:
1. Pre-clinical development is research carried out in lab assays and on animals. It includes:
– Identification (discovery) of relevant antigens (e.g. screening)
– Creation of the vaccine concept
– Evaluation of vaccine efficacy in test tubes and animals
– Manufacture of the vaccine to Good Manufacturing Practice standards
2. Clinical development is when the vaccine is first tested in humans. It covers four stages over several years, from initial clinical trials in humans (phase I) right through to introduction and beyond (phase IV). Clinical development is built on rigorous ethical principles of informed consent from volunteers, with an emphasis on vaccine safety as well as efficacy.

Update EMA on Treatments and Vaccines against COVID-19 under Development

vaccines
EMA’s COVID-19 response team has been in contact with developers of around 40 therapeutic medicines, allowing better understanding of potential treatments. However, at this point, on the basis of the ...

Johnson & Johnson Announces a Lead Vaccine Candidate for COVID-19

Johnson & Johnson announced the selection of a lead COVID-19 vaccine candidate from constructs it has been working on since January 2020. The Company expects to initiate human clinical studies of ...

Chinese Trial Vaccine Against COVID-19 May Be Tested Abroad

The first stage clinical trial for the vaccine was started in Wuhan on March 16 after authorities approved. It has been proceeding smoothly, and its results will be published in April, said Chen Wei, ...

Russia’s Medical Biological Agency Has Developed 7 Vaccine Prototypes against COVID-19

"As of today, the Federal Medical Biological Agency has developed seven prototypes of a genetically engineered vaccine assembled from fused proteins, with each of them having epitopes, i.e. parts that...

Boris Johnson Announced Record Funding to Find a Coronavirus Vaccine

influenza vaccine
The race to find a vaccine for coronavirus will be boosted by £210 million of new UK aid funding, the Prime Minister announced 26th March following a virtual summit of G20 leaders. To date, this is...

Data Requirements for Phase 1 COVID-19 Vaccine Trials

Global regulators have published a report presenting the outcomes of a workshop on COVID-19 vaccine development that was convened under the umbrella of the International Coalition of Medicines Regulat...

The Biopharma Produced Virus-Like Particles of the Coronavirus Using Plant-based Technology

Medicago, a biopharmaceutical company headquartered in Quebec City, announced that they have successfully produced a Virus-Like Particle (VLP) of the coronavirus just 20 days after obtaining the SARS-...

Coronavirus vaccine project launched in Kazan

The project is funded by Nonprofit Organization DNA Research Center. Kazan Federal University has started to search for a vaccine solution, said Professor Albert Rizvanov, Director of the Center fo...

Russian Coronavirus Vaccine to Be Tested on Lab Animals

Novosibirsk’s Vector Institute, which has developed a prototype of the coronavirus vaccine, will test it first on the most sensitive lab animals - lower primates and ferrets, Vector Institute Deputy C...

EC Has Announced €80 Million of Support to CureVac for COVID-19 Vaccine Development

The European Commission (EC) has offered €80 million of financial support to CureVac, a German biopharmaceutical company and vaccine developer, to aid in the scale-up of R&D and production of a va...

BIOCAD Begins Developing COVID-19 Vaccine

Biocad, a pharmaceutical company based in Russia's St. Petersburg, has joined the quest for developing a vaccine against the novel coronavirus strain that triggered the COVID-19 pandemic, and will use...

Pfizer and Biotech Will Jointly Develop Vaccine to Prevent COVID-19

lab research
Pfizer Inc. and BioNTech SE announced that the companies have agreed to a letter of intent regarding the co-development and distribution (excluding China) of a potential mRNA-based coronavirus vaccine...

CanSino Bio is Starting Human Testing of a Recombinant Vaccine Against COVID-19

Among a long list of biopharma companies developing vaccines against the novel coronavirus, China’s CanSino Biologics and Massachusetts-based Moderna Therapeutics are so far the frontrunners. CanSi...

$2 billion Required to Support the Development of a Vaccine Against COVID-19

The Coalition for Epidemic Preparedness Innovations (CEPI), the organisation set up to accelerate the development of vaccines against emerging infectious diseases, has made an urgent call for $2 billi...

Production of First Portable coronavirus test in Russia to begin in April

The world’s first portable coronavirus test system is slated for production in April, Russian President Vladimir Putin said during his meeting with the Cabinet. "The Russian Direct Investment Fund wi...

The First Clinical Trial for a Vaccine to COVID-19 Began in USA

Inside the U.S., the first clinical trial for a vaccine to the novel coronavirus that causes COVID-19 began. It is mRNA-1273, developed by Moderna with the National Institute of Allergy and Infectious...