Tag: Development of Vaccines

Development of vaccines can be simplified into two broad stages:
1. Pre-clinical development is research carried out in lab assays and on animals. It includes:
– Identification (discovery) of relevant antigens (e.g. screening)
– Creation of the vaccine concept
– Evaluation of vaccine efficacy in test tubes and animals
– Manufacture of the vaccine to Good Manufacturing Practice standards
2. Clinical development is when the vaccine is first tested in humans. It covers four stages over several years, from initial clinical trials in humans (phase I) right through to introduction and beyond (phase IV). Clinical development is built on rigorous ethical principles of informed consent from volunteers, with an emphasis on vaccine safety as well as efficacy.

Development of Micromotors for Oral Vaccines Delivery

Researchers have developed a method of using micromotors to deliver oral vaccines in an attempt to break away from widely used injections. Millions of lives around the world have been saved through...

WuXi Biologics entered into partnership with AC Immune

WuXi Biologics and AC Immune SA announced the first steps of an exclusive strategic collaboration that covers biologics discovery, development and manufacturing.

Researchers conducted first trial of personalized vaccine for brain cancer

personalized medicine
Clinical study demonstrates proof-of-concept of the Glioma Actively Personalized Vaccine Consortium approach in a pioneering multi-center, multi-national study co-funded by the European Union.

MSD and Instituto Butantan to collaborate on dengue vaccine

MSD and Instituto Butantan, a non-profit producer of immunobiologic products announced a collaboration agreement to develop vaccines against dengue virus disease, the mosquito-borne infection.

Genetic Immunity presented its immunotherapy platform in Russia

clinical trials
Genetic Immunity announced that it was invited to present at the first Russian-Chinese HIV Congress in Moscow (Russia).

Scientists created a temperature-stable polio vaccine

lab research
Researchers from The Keck School of Medicine of the University of Southern California (USA) have developed a polio vaccine that doesn’t require refrigeration.

Seqirus seeks European approval for its influenza vaccine

Seqirus, a global leader in influenza prevention, announced that its cell-based quadrivalent influenza vaccine has received a positive opinion from the European Medicines Agency (EMA).

DNAtrix and Valo Therapeutics to develop a novel vaccine for cancer therapy

DNAtrix (USA) and Valo Therapeutics (Finland) announced an exclusive R&D collaboration to develop enhanced vaccines using DNAtrix's clinical stage viruses and Valo's antigenic peptide technology.

US scientists reports of promising studies on peptide-based cancer vaccine

The peptide-based vaccine targets specific enzymes called metalloproteinases (MMPs) that are necessary for any cancer to grow tumors, metastasize, and form blood vessels in tumors (angiogenesis).

Universal flu vaccine candidate shows promising results in preclinical studies

influenza vaccine
InvVax in collaboration with Trudeau Institute Contract Research Organization and Hong Kong University, announced that it has demonstrated preclinical success for its universal flu vaccine candidate.

Johnson & Johnson launches a new vaccines facility in the Netherlands

Johnson & Johnson unveiled a new vaccines launch facility that represents a significant investment in novel vaccines development, global health and security, and pandemic preparedness efforts.

GlycoBac starts new partnership with MilliporeSigma

GlycoBac, a University of Wyoming spin-out biotechnology company, and MilliporeSigma recently partnered to offer a rhabdovirus-free insect platform for viral vaccines and gene therapy development.

Themis Bioscience signs licensing agreement with Max-Planck-Innovation

Themis announced that it has entered into a license agreement with Max-Planck-Innovation GmbH, the technology transfer agency of the Max Planck Society in Germany.

Russian TB vaccine has successfully completed preclinical studies

Minister of Health of the Russian Federation Veronika Skvortsova made an announcement on the Margins of UN General Assembly.

GSK’s experimental TB vaccine shows promising results in clinical trials

GSK and Aeras reported that GSK’s M72/AS01E candidate vaccine significantly reduced the incidence of pulmonary tuberculosis disease in HIV-negative adults with latent tuberculosis infection.

Russian powder vaccine can be transported in a conventional refrigerator

A new form of vaccine against Ebola fever has been developed in Russia, Veronica Skvortsova, the head of the department, said at a meeting with the wife of the President of the Republic of Guinea.