Tag: Development of Vaccines

Development of vaccines can be simplified into two broad stages:
1. Pre-clinical development is research carried out in lab assays and on animals. It includes:
– Identification (discovery) of relevant antigens (e.g. screening)
– Creation of the vaccine concept
– Evaluation of vaccine efficacy in test tubes and animals
– Manufacture of the vaccine to Good Manufacturing Practice standards
2. Clinical development is when the vaccine is first tested in humans. It covers four stages over several years, from initial clinical trials in humans (phase I) right through to introduction and beyond (phase IV). Clinical development is built on rigorous ethical principles of informed consent from volunteers, with an emphasis on vaccine safety as well as efficacy.

Themis Bioscience signs licensing agreement with Max-Planck-Innovation

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Themis announced that it has entered into a license agreement with Max-Planck-Innovation GmbH, the technology transfer agency of the Max Planck Society in Germany.

Russian TB vaccine has successfully completed preclinical studies

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Minister of Health of the Russian Federation Veronika Skvortsova made an announcement on the Margins of UN General Assembly.

GSK’s experimental TB vaccine shows promising results in clinical trials

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GSK and Aeras reported that GSK’s M72/AS01E candidate vaccine significantly reduced the incidence of pulmonary tuberculosis disease in HIV-negative adults with latent tuberculosis infection.

Russian powder vaccine can be transported in a conventional refrigerator

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A new form of vaccine against Ebola fever has been developed in Russia, Veronica Skvortsova, the head of the department, said at a meeting with the wife of the President of the Republic of Guinea.

LineaRx will develop cancer vaccines aided by Italian biotech

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LineaRx, a subsidiary of Applied DNA Sciences, has entered into a Joint Development Agreement with Takis SRL and Evvivax SLR. They will focus on developing anti-cancer vaccines.

Nacimbio completed Phase I clinical trials of the rotavirus vaccine

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Nacimbio has completed the first phase of clinical trials of the rotavirus vaccine. The new drug will be packaged in Russia in 2020 already, while the full production cycle will be launched in 2026.

US scientists conduct clinical trial of influenza vaccine with imiquimod

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A Phase 1 clinical trial examining whether a topical cream can enhance the immune response conferred by a “pre-pandemic” influenza vaccine is underway at Baylor College of Medicine in Houston (USA).

Researchers are testing new cancer vaccine against melanoma

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An experimental cancer vaccine that boosts the immune system’s ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumors.

SGS boosts its capabilities in infectious disease therapeutics and vaccines

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SGS announced that it has successfully implemented advanced techniques for the collection and use of Peripheral Blood Mononuclear Cells (PBMCs) for early phase clinical trials.

First clinical trial of live attenuated Zika virus vaccine is launched in USA

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Vaccinations have begun in a first-in-human trial of an experimental live, attenuated Zika virus vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases (USA).

BioNTech will cooperate with Pfizer on mRNA-based flu vaccines

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BioNTech AG announced that it has entered into a multi-year research and development (R&D) collaboration with Pfizer to develop mRNA-based vaccines for prevention of influenza.

Cuban veterinary vaccine broadens its market

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In the last eight years the Cuban vaccine against cattle tick developed by the Center for Genetic Engineering and Biotechnology has produced incomes for more than 20 million dollars to the country.

Scientists from Scripps Research engineered a new antibody analysis system

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The new system lets scientists quickly assess the full spectrum of antibodies produced in an individual in response to a pathogen or vaccine and determine if these antibodies are likely to be effective.

Moderna Therapeutics launches new manufacturing facility

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Moderna Therapeutics, a clinical-stage biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, announced the opening of its manufacturing facility in Norwood, Massachusetts (USA).

Innovest Global launches its Biotech and Health Services division

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Innovest Global launched its anticipated Biotechnology & Health Services Division with the acquisition of a twenty percent interest in StemVax Therapeutics.

Seqirus joined the Universal Influenza Vaccine Initiative

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The Human Vaccines Project, a nonprofit public-private partnership, and Seqirus, a global leader in the prevention of influenza, announced that Seqirus is joining the Project's Universal Influenza Vaccine Initiative.