Tag: Antibiotics

Antibiotics, also called antibacterials, are a type of antimicrobial drug used in the treatment and prevention of bacterial infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza, and their inappropriate use allows the emergence of resistant organisms. Drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics.
Sometimes the term antibiotic (which means “opposing life”) is used to refer to any substance used against microbes, synonymous with antimicrobial. Some sources distinguish between antibacterial and antibiotic; antibacterials are used in soaps and disinfectants, while antibiotics are used as medicine. Antibiotics revolutionized medicine in the 20th century, and have together with vaccination led to the near eradication of diseases such as tuberculosis in the developed world. However, their effectiveness and easy access led to overuse, especially in livestock raising, prompting bacteria to develop resistance. This has led to widespread problems with antimicrobial and antibiotic resistance, so much as to prompt the World Health Organization to classify antimicrobial resistance as a “serious threat [that] is no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country”. All classes of antibiotics in use today were first discovered prior to the mid 1980s.

Sales of veterinary antimicrobials in Europe decreased by about 20%

A new report published by European Medicines Agency (EMA) shows that the overall sales of veterinary antimicrobials across Europe have decreased by more than 20% between 2011 and 2016.

Paratek Pharmaceuticals seeks EMA approval for its novel antibiotic

Paratek Pharmaceuticals (USA) announced the acceptance of the submission to the European Medicines Agency (EMA) of the Marketing Authorization Application (MAA) for omadacycline.

Boston Pharmaceuticals licenses three anti-infective programs from Novartis

antimicrobial resistance
Novartis has entered into a licensing and equity agreement with Boston Pharmaceuticals for the development of three novel anti-infective drug candidates.

Dr Reddy’s sells its US manufacturing facility to UAE pharma company

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Dr Reddy’s Laboratories has sold the antibiotics manufacturing facility and related assets it had acquired in Bristol, Tennessee (USA), from GlaxoSmithKline (GSK) seven years ago.

GARDP and Novartis to cooperate on enhancing generic antibiotics

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The Global Antibiotic Research & Development Partnership (GARDP) and Novartis are joining forces to accelerate the development and availability of generic antibiotic treatments for children.

Genentech antibiotic displays high activity against superbugs

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Recently published findings demonstrate that optimized arylomycin analogues could translate into new therapies to address the growing threat of multidrug-resistant Gram-negative infections.

Bioengineers discovered promising antibiotic candidates

Researchers from The Massachusetts Institute of Technology and the University of Naples Federico II found that fragments of the protein pepsinogen can kill bacteria such as Salmonella and E. coli.

CFU scientists develop phytobiotics from Crimean wild plants

Phytobiotics, a biologically active substance isolated from plants, can become a real alternative to antibiotics, improve the immunity of patients and fight hospital infections

Phico Therapeutics receives support to develop its intravenous antibiotic

Phico Therapeutics announced that it had been awarded significant funding to support the manufacturing development of its intravenous antibiotic, SASPject PT3.8.

Wockhardt launches new manufacturing facility in Dubai

Wockhardt, a global pharmaceutical company, has expanded into the Middle East with the opening of a $40 million state-of-the-art facility for manufacturing new chemical entities in Dubai, UAE.

Belarusian drugs are preparing to enter the US market

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Belarusian medications are entering new markets. They will be marketed in the US. As for the European Union, one Belarusian plant has already received permission.

Nabriva buys Zavante Therapeutics and its late-stage antibiotic drug

Nabriva Therapeutics, a clinical stage biopharmaceutical company acquired Zavante Therapeutics, a biopharmaceutical company focused on developing novel therapies to improve the outcomes of hospitalized patients.

British scientists launched new open-access database called AntibioticDB

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The new resource is the result of a collaboration between the University of Birmingham, the John Innes Centre and the British Society for Antimicrobial Chemotherapy.

Boston College researchers made a step towards targeted antibiotics

The approach of Boston College scientists maps, ranks, and identifies where antibiotic sensitivity functions reside in the genome of strains of S. pneumoniae.

A study on prevalence of antibiotic resistance was conducted in Russia

Antimicrobial resistance
GSK published the results of its Survey of Antibiotic Resistance in Russia. The collected data revealed high sensitivity of the main bacteria causing respiratory infections to amoxicillin/clavulanate and fluoroquinolones.

Russia may simplify registration of new antibiotics

This was announced by Sergey Glagolev, the Head of the Division for Monitoring the Efficacy and Safety of Medical Products, the Department of the State Quality Control of Medical Products of Roszdravnadzor.