Novartis buys exclusive rights to a promising dermatologic drug

| By | Drug Development, Novartis, Pharmaceutical Deal
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Novartis announced that it has entered into an exclusive license agreement with biotech companies Galapagos NV, Mechelen (Belgium) and MorphoSys AG, Planegg/Munich (Germany) regarding their compound MOR106.

Under the agreement, Novartis acquires the exclusive global development and marketing rights to MOR106 for atopic dermatitis and all other potential indications. Novartis will make an upfront payment of €95 million to Galapagos and MorphoSys, and additional payments, royalties and fees pending achievement of agreed milestones.

AD, a form of eczema, is a dermatologic disease that can cause intense itching and recurring lesions. AD affects approximately 8% of adults and 14% of children worldwide. There is significant medical need for innovative treatments to help patients with this debilitating disease.

MOR106 is a monoclonal antibody directed against IL-17C. MOR106 is an extension of the Novartis AD portfolio, which includes oral ZPL389 in phase II. MOR106 has demonstrated first signs of efficacy and was generally safe and well tolerated in a double blind placebo-controlled Phase Ib study. MOR106 is a potentially first in class anti-IL-17C monoclonal antibody for AD and possibly other diseases.

The in-licensing of MOR106 underlines Novartis commitment to lead immuno-dermatology, adding to Novartis marketed product portfolio Cosentyx and Xolai.

SOURCE: novartis
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