Akebia Therapeutics and Keryx Biopharmaceuticals will merge

| By | Drug Development, Pharmaceutical Deal
0
161

Akebia Therapeutics and Keryx Biopharmaceuticals announced that the companies signed, and the boards of directors of both companies have unanimously approved, a definitive merger agreement under which the companies will combine in an all-stock merger.

The transaction will create a fully integrated biopharmaceutical company focused on chronic kidney disease (CKD), with an implied pro forma equity value of approximately $1.3 billion. The combined company will be named Akebia Therapeutics, Inc.

John P. Butler, President and Chief Executive Officer of Akebia, is expected to lead the combined company, and Keryx will appoint the Chairperson of the Board of Directors of the combined company.

The merger of Akebia and Keryx creates a renal-focused company committed to developing and delivering innovative therapeutic products. Keryx’s Auryxia® (ferric citrate) is a U.S. Food and Drug Administration (FDA)-approved medicine to treat dialysis dependent CKD patients for hyperphosphatemia and non-dialysis dependent CKD patients for iron deficiency anemia (IDA). Akebia’s vadadustat is an investigational Phase 3 oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) with the potential to advance the treatment of patients with anemia due to CKD, many of whom are currently receiving injectable erythropoietin-stimulating agents (ESAs).

The companies believe that Auryxia and vadadustat, if FDA-approved, have the potential to deliver an all-oral treatment approach for patients with anemia due to CKD. More broadly, the combined company has the potential to offer therapeutic options to patients across all stages of CKD, including non-dialysis dependent and dialysis dependent patients, and to become a partner of choice for the renal community and for companies developing renal products.

Keryx Biopharmaceuticals, headquartered in Boston (USA), is focused on the development and commercialization of innovative medicines that provide unique and meaningful advantages to people with kidney disease.

Akebia Therapeutics is a biopharmaceutical company headquartered in Cambridge, Massachusetts (USA), focused on delivering innovative therapies to patients with kidney disease through hypoxia-inducible factor biology.

SOURCE: akebia
SHARE
GMP news
Pharmaceutical industry News and events. Technology transfer and contract manufacturing of medicines.