Evotec AG, a drug discovery alliance and development partnership company, announced that it has expanded its CRISPR service offering with the addition of a licence from ERS Genomics Limited. With this licence, Evotec gains access to the leading technology for gene editing, thereby complementing and expanding its existing service offering in the CRISPR gene editing space.
The new licence from ERS Genomics Limited complements and expands Evotec’s existing CRISPR licences through the Broad Institute with gene editing technology from Emmanuelle Charpentier and others.
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a naturally occurring bacterial immune system. Researchers have harnessed this system as a genome editing tool for mammalian cells. Evotec has multiple licences to this technology through ERS Genomics and the Broad Institute for the use of the CRISPR-Cas9 gene editing technology.
Evotec uses the CRISPR technology to drive its target identification platform as well as aid the deconvolution of targets from phenotypic screening. With the integration of genome-wide arrayed CRISPR libraries into Evotec’s screening platforms, Evotec is harnessing the power of gene deletion and human, cell-based disease models to identify novel targets for downstream drug discovery programmes.
ERS Genomics was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property held by Dr Emmanuelle Charpentier. Non-exclusive licences are available for research and sale of products and services across multiple fields including: research tools, kits, reagents; discovery of novel targets for therapeutic intervention; cell lines for discovery and screening of novel drug candidates; GMP production of healthcare products; production of industrial materials such as enzymes, biofuels and chemicals; and synthetic biology.