Emulate and AstraZeneca will jointly develop Organs-on-Chips technology

| By | AstraZeneca, Drug Development, R&D
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Emulate, Inc. has formed a collaborative partnership with AstraZeneca’s Innovative Medicines and Early Development (IMED) Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.

As part of the agreement, Emulate plans to co-locate scientists within AstraZeneca’s laboratories. The aim of this agreement is to accelerate the development of Organs-on-Chips technology and testing within the context of a pharmaceutical organization.

AstraZeneca began collaborating on Emulate’s Organs-on-Chips technology in 2013, and the two companies have successfully published some of their recent work during the Society of Toxicology meeting in March 2018. The Organs-on-Chips technology comprises of the Organ-Chips, instrumentation, and software apps. In the future, the system is also expected to reduce the use of animals in research as well as the cost and time of discovery and development.

An initial focus will be to use Emulate’s Liver-Chip for safety testing of drug candidates across the AstraZeneca pipeline with the goal of submitting Organ-Chip data within the regulatory framework for new drugs. The terms of the agreement also allow for Emulate’s technology to be adopted across AstraZeneca’s therapeutic areas and will enable the two companies to develop functionality of three other Emulate Organ-Chips — the Lung Tumor-Chip, Lung-Chip, and Glomerulus Kidney-Chip. By delivering new insights into human disease mechanisms, scientists will be more equipped to predict the clinical relevance of candidate drug safety and efficacy.

Based in Boston, Massachusets (USA), Emulate, Inc. is a private company focused on commercializing Organs-on-Chips as an automated human bioemulation platform that achieves a new standard for mimicking true human physiology so that responses to medicines, chemicals and diseases can be accurately predicted.

SOURCE: business wire
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