Researchers at the Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences synthesized a substance that protects against flu virus, including H1N1, better known as swine flu.
According to Yana Kostyra, the Senior Researcher of Pharmaceutical Design Team at the Institute and the Candidate of Pharmaceutical Sciences, the development of substance began in 2013.
At the end of 2017, the Irkutsk Institute of Chemistry was granted a patent by the Russian Federal Service for Intellectual Property for a method to obtain an agent possessing antiviral activity.
“While working on the modification of carbohydrates extracted from vegetable raw materials and synthesized by microorganisms, we obtained a modified oligosaccharide with a pronounced antiviral activity,” said Ms. Kostyra.
The researchers at the Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences (Novosibirsk) tested this activity in cell culture and in mice. Test results demonstrated that the substance exerted a very good preventive effect, as the mice challenged with flu virus after the intranasal substance administration remained healthy.