ImmunoQure, a German biotech company focused on the research and development of human autoantibodies as therapeutics for the treatment of common human diseases, and the international pharmaceutical company Servier announced the establishment of a Worldwide, exclusive partnership for the development of a therapeutic autoantibody neutralizing interferon-alpha.
ImmunoQure works in collaboration with leading academic centres and the APECED Oy patient support group to gain a greater understanding of an ultra-rare disease termed APECED/APS-1. APS-1 is a monogenetic disorder whereby null or hypomorphic mutations in the AIRE gene greatly impair central T cell tolerance.
ImmunoQure and Servier will work collaboratively to advance ImmunoQure’s therapeutic human Interferon-alpha autoantibody through preclinical development and into the clinic where Servier will assume all responsibilities for its development as therapeutic to treat diseases driven by elevated levels of interferon-alpha, with emphasis on systemic lupus erythemathosus and Sjögren’s syndrome.
Dr. Edward Stuart, co-founder and Chairman of the Board of ImmunoQure commented, “The industry currently faces a number of pressing issues including the need for novel, innovative and safe drug candidates to fill pipelines. Our scientific and business approach provides one solution to such issues. Together with our partner Servier and our academic partners such as the King’s College London, and the Universities of Helsinki and Tartu, we are ideally positioned to bring ImmunoQure’s outstanding science forward.”