Takeda Pharmaceutical Company Limited and Noile-Immune Biotech Inc. announced that they have entered into a collaboration to develop next generation chimeric antigen receptor T cell therapy (CAR-T).
The next generation CAR-T cell therapy was developed by Professor Koji Tamada at Yamaguchi University and Noile-Immune has exclusive license for this platform technology. The CAR-T therapy produces cytokines, chemokines, and other molecules, which is expected to potentially influence or alter the tumor microenvironment of solid tumor tissues to enhance the anti-tumor effect of the therapy. The companies intend to use this technology to discover and develop new CAR-T cell immunotherapies, with the aim of treating a broad range of cancers.
The collaboration between Takeda and Noile-Immune Biotech will accelerate research and development of CAR-T cell therapy. In addition to providing resources required for implementation, Takeda will make a technology access payment to Noile-Immune Biotech and additionally Takeda will make an equity investment. Takeda will have exclusive options to obtain licensing rights for the development and commercialization of Noile-Immune’s pipeline and products resulting from this partnership on pre-agreed terms. Additional terms of this agreement are not disclosed.
“This technology forms the basis for developing potentially transformational treatments for solid tumors,” said Dr. Hidenobu Ishizaki, President of Noile-Immune. “The platform was developed by our founder, director, and CSMO, Professor Koji Tamada at the Department of Immunology at Yamaguchi University Graduate School of Medicine. We believe our collaboration with Takeda is a significant step towards rapidly delivering therapies that use this technology to cancer patients.”